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Article

[Advances in the pathogenesis, biology, and management of multiple myeloma].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 1996

Kosaka M

Abstract excerpt

There have been several advances in our understanding and management of multiple myeloma (MM). Firstly, somatic mutations without intraclonal variation have been detected in Ig genes of malignant plasma cells, indicating that the major oncogenic events yielding continuous proliferation of the myeloma stem cell occur in a cell selected by contact with antigen in the lymphoid follicles. Secondly, interleukin-6...

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PMID: 8816060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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