Article
Renal allograft immune response is influenced by patient and donor cytokine genotypes.
Transplantation proceedings - 1 Jan 2000
Canossi A, Piazza A, Poggi E, Ozzella G, Di Rocco M, Papola F, Iaria G, Adorno D
Abstract excerpt
This study investigated the impact of specific cytokine genotypes on the incidence of acute rejection episodes (ARE), chronic graft dysfunction (CGD), and anti-HLA donor-specific antibody (DS-Ab) production in 86 renal transplant recipients and 70 cadaveric donors. A PCR-SSP method was performed for the analysis of polymorphisms in TNF-alpha, IL-6, TGF-beta, IL-10, and IFN-gamma cytokines. DS-Ab monitoring of...
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