Article
Relationship between angiotensin-converting enzyme gene polymorphism and insulin resistance in never-treated hypertensive patients.
The Journal of clinical endocrinology and metabolism - 1 Jan 2001
Perticone F, Ceravolo R, Iacopino S, Cloro C, Ventura G, Maio R, Gulletta E, Perrotti N, Mattioli P L
Abstract excerpt
The association between angiotensin-converting enzyme (ACE) gene polymorphism and insulin resistance (IR) in hypertensive subjects remains controversial. Thus, we evaluated the possible association between IR and ACE gene polymorphism in a group of hypertensive, never-treated patients compared with that in a normotensive control group. We enrolled 200 (114 men and 86 women; age, 45.5 +/- 4.7 yr) hypertensive...
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