Article
Insulin resistance and angiotensin converting enzyme polymorphism in Japanese hypertensive subjects.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 1999
Yamamoto J, Kageyama S, Sakurai T, Ishibashi K, Mimura A, Yokota K, Aihara K, Taniguchi I, Yoshida H, Tajima N
Abstract excerpt
Renin-angiotensin system activity has been shown to affect insulin sensitivity. However, the relationship between I/D polymorphism and insulin resistance is controversial. Therefore, we examined the relationship between the ACE genotype and insulin sensitivity in 51 Japanese hypertensive patients using the glucose clamp technique. The ACE genotype distribution in the hypertensive subjects was: 7 subjects with DD,...
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