Article
Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation.
Mechanisms of development - 1 Mar 2001
Wu X, Wu J, Huang J, Powell W C, Zhang J, Matusik R J, Sangiorgi F O, Maxson R E, Sucov H M, Roy-Burman P
Abstract excerpt
To facilitate the elucidation of the genetic events that may play an important role in the development or tumorigenesis of the prostate gland, we have generated a transgenic mouse line with prostate-specific expression of Cre recombinase. This line, named PB-Cre4, carries the Cre gene under the control of a composite promoter, ARR2PB which is a derivative of the rat prostate-specific probasin (PB) promoter. Based...
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