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Article

Interaction of stilbene disulphonates with cloned K(ATP) channels.

British journal of pharmacology - 1 Mar 2001

Proks P, Jones P, Ashcroft F M

Abstract excerpt

In this study, we tested the effects of the stilbene disulphonates DIDS and SITS on three different types of cloned K(ATP) channel (Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2DeltaC) heterologously expressed in Xenopus oocytes, with the aim of identifying the part of the channel which is involved in mediating disulphonate inhibition. We found that the inhibitory site(s) for these drugs lies within the Kir6.2 subunit of...

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Identifiers

PMID: 11226127
DOI: 10.1038/sj.bjp.0703916
PMCID: PMC1572654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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