Article
The androgen receptor and genetic susceptibility to ovarian cancer: results from a case series.
Cancer research - 1 Feb 2001
Levine D A, Boyd J
Abstract excerpt
Our objectives were to test whether polymorphic variation in the (CAG)n repeat of the androgen receptor (AR) gene affects penetrance of germ-line BRCA mutations for ovarian cancer or age of diagnosis for ovarian cancer. Using a case-series study design, 179 consecutive Ashkenazi Jewish ovarian cancer patients were genotyped for AR repeat length and BRCA mutation status. There was no association between AR repeat...
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