Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of thrombospondin-1 in human hepatocarcinoma cell lines and its regulation by transcription factor Jun/AP-1.

Molecular and cellular biochemistry - 1 Jan 2001

Kim S A, Um S J, Kang J H, Hong K J

Abstract excerpt

Thrombospondin-1 (TSP-1) is a homotrimeric glycoprotein synthesized in a variety of normal and transformed cells, and secreted into the extracellular matrix. Based on its known effects on the tumor and endothelial cells, TSP-1 was implicated in the tumor growth and metastasis. In the present study, we have demonstrated the expression of TSP-1 in the human hepatocarcinoma cell lines. TSP-1 was detected in human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Carcinogens
Share to Luciferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Kinase C

Share to Proto-Oncogene Proteins c-jun

Share to Tetradecanoylphorbol Acetate

Share to Thrombospondin 1

Share to Transcription Factor AP-1

Source

Identifiers

PMID: 11216860
DOI: 10.1023/a:1011022822077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of thrombospondin-1 in human hepatocarcinoma cell lines and its regulation by transcription factor Jun/AP-1.PMID 11216860Read ↗

A novel thrombospondin-1 transcript exhibits distinctive expression and activity in thyroid tumorigenesisSemantic proximity Read ↗

Thyroid Hormone Receptors Suppress Pituitary Tumor Transforming Gene 1 Activity in HepatomaSemantic proximity Read ↗

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members.Semantic proximity Read ↗

Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteins.Semantic proximity Read ↗

Regulation of the transcriptional activation of CTRP3 in chondrocytes by c-Jun.Semantic proximity Read ↗

Gene expression and transcriptional regulation of thrombopoietin.Semantic proximity Read ↗

Identification of human hepatic stimulator substance gene promoter and demonstration of dual regulation of AP1/AP4 cis-acting element in different cell lines.Semantic proximity Read ↗

Regulation of differentiation- and proliferation-inducers on Lewis antigens, alpha-fucosyltransferase and metastatic potential in hepatocarcinoma cells.Semantic proximity Read ↗

c-Jun Transactivates the Promoter of the Human p21 Gene by Acting as a Superactivator of the Ubiquitous Transcription Factor Sp1Semantic proximity Read ↗

Influence of the content in transcription factors on the phenotype of mouse hepatocyte-like cell lines (mhAT).Semantic proximity Read ↗

Forskolin up-regulates metastasis-related phenotypes and molecules via protein kinase B, but not PI-3K, in H7721 human hepato-carcinoma cell line.Semantic proximity Read ↗

Characterization of the human protein S gene promoter: a possible role of transcription factors Sp1 and HNF3 in liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.