Article
Forskolin up-regulates metastasis-related phenotypes and molecules via protein kinase B, but not PI-3K, in H7721 human hepato-carcinoma cell line.
Molecular and cellular biochemistry - 1 Dec 2003
Wu Shi-liang, Ma Jun, Qi Hui-ling, Zhang Ying, Zhang Xia-ying, Chen Hui-li
Abstract excerpt
Forskolin (FSK) is known as an up-regulator of intracellular cAMP and inhibitor of cancer growth and metastasis. The effects of FSK on the metastasis potential and its mechanisms were studied using a human hepatocarcinoma cell line, H7721. It was found that FSK stimulated cell growth, increased c...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
