Article
Methadone maintenance treatment: is it possible to adapt the daily doses to the metabolic activity of the patient?
Therapeutic drug monitoring - 1 Feb 2001
Charlier C, Dessalles M C, Plomteux G
Abstract excerpt
Controversy still exists concerning the proper daily dose of methadone to be used in opiate dependency treatment. Because it is admitted that serum methadone concentration may be significantly correlated with the amount of drug available at the receptor level, it could be interesting to predict the methadone daily doses necessary to reach such a serum concentration. The authors have attempted to correlate the...
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