Article
Galectin-3 modulates ureteric bud branching in organ culture of the developing mouse kidney.
Journal of the American Society of Nephrology : JASN - 1 Mar 2001
Bullock Simon L, Johnson Tanya M, Bao Q I, Hughes R Colin, Winyard Paul J D, Woolf Adrian S
Abstract excerpt
Galectin-3 is a mammalian beta-galactoside-specific lectin with functions in cell growth, adhesion, and neoplastic transformation. On the basis of expression patterns in humans, it is proposed that galectin-3 modulates fetal collecting duct growth. This article provides evidence that galectin-3 can modulate branching morphogenesis of the mouse ureteric bud/collecting duct lineage. With the use of...
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