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Article

Repression of CD2 gene expression is mediated by an AP-2 related factor.

Biochemical and biophysical research communications - 23 Feb 2001

Outram S V, Grimwade D, Crompton T

Abstract excerpt

Tissue specific and developmental expression of the CD2 gene is tightly regulated during T cell development. DNase I hypersensitivity analysis has revealed the presence of two sites (DHS1 and 2) located 5' to the CD2 gene which have been reported to be implicated in the developmental regulation of expression of CD2. The location of DHS2 marks the position of the minimal promoter whereas DHS1 is located...

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Identifiers

PMID: 11181063
DOI: 10.1006/bbrc.2001.4373

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