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Article

Relative fitness of carriers of the mitochondrial DNA mutation 3243A > G.

European journal of human genetics : EJHG - 1 Jan 2001

Moilanen J S, Majamaa K

Abstract excerpt

Deleterious point mutations in mitochondrial DNA (mtDNA) have been found in many human populations and always at a low frequency suggesting that they are under strong negative selection. It is assumed that this selection is caused by reduced genetic fitness of mutation carriers, but the fitness of carriers of any mtDNA mutation has not been determined. We estimated the reproductive disadvantage caused by the...

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PMID: 11175302
DOI: 10.1038/sj.ejhg.5200550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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