Article
Expression of a candidate gene for the gonadoblastoma locus in gonadoblastoma and testicular seminoma.
Cytogenetics and cell genetics - 1 Jan 2000
Lau Y, Chou P, Iezzoni J, Alonzo J, Kömüves L
Abstract excerpt
The gonadoblastoma locus on the Y chromosome (GBY) predisposes the dysgenetic gonads of XY females to develop in situ tumors. It has been mapped to a critical interval on the short arm and adjacent centromeric region on the Y chromosome. Currently there are five functional genes identified on the GBY critical region, thereby providing likely candidates for this cancer predisposition locus. To evaluate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
