Article
Molecular mapping of the putative gonadoblastoma locus on the Y chromosome.
Genes, chromosomes & cancer - 1 Nov 1995
Salo P, Kääriäinen H, Petrovic V, Peltomäki P, Page D C, de la Chapelle A
Abstract excerpt
Based on the high incidence of gonadoblastoma in females with XY gonadal dysgenesis or 45,X/46,XY mosaicism, the existence of a susceptibility locus on the Y chromosome (GBY) has been postulated. We attempted to map GBY by making use of a recently developed dense map of Y-chromosomal sequence-tagged sites (STSs). In two female patients with gonadoblastoma, small marker chromosomes contained portions of the Y...
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