Article
HLA complex genes in type 1 diabetes and other autoimmune diseases. Which genes are involved?
Trends in genetics : TIG - 1 Feb 2001
Undlien D E, Lie B A, Thorsby E
Abstract excerpt
The predisposition to develop a majority of autoimmune diseases is associated with specific genes within the human leukocyte antigen (HLA) complex. However, it is frequently difficult to determine which of the many genes of the HLA complex are directly involved in the disease process. The main reasons for these difficulties are the complexity of associations where several HLA complex genes might be involved, and...
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