Article
Novel gene associations in type 1 diabetes.
Current diabetes reports - 1 Oct 2010
Ilonen Jorma, Hermann Robert
Abstract excerpt
Recent genome-wide association studies have been able to identify multiple new gene loci affecting type 1 diabetes susceptibility, but the impact of these new defined loci seems to decrease in parallel with their number. The HLA gene region remains the main nominator of genetic susceptibility, although the identity of important genes and especially the mechanisms of their action are still largely unclear....
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