Article
Molecular biology of prostate-cancer pathogenesis.
Current opinion in urology - 1 May 2006
Shand Randi L, Gelmann Edward P
Abstract excerpt
PURPOSE OF REVIEW: The genetic and molecular basis of prostate-cancer pathogenesis is reviewed. RECENT FINDINGS: Several genetic loci have been found that are associated with hereditary predisposition to prostate cancer, but they account for a small fraction of all cases. A number of suppressor genes have been identified that are activated by either complete or partial genetic loss in sporadic prostate cancer....
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