Article
Immune responses following simian/human immunodeficiency virus (SHIV) challenge of rhesus macaques after human immunodeficiency virus (HIV)-1 third variable domain (V3) loop-based genetic immunization.
Journal of medical primatology - 1 Dec 2000
Le Borgne S, Le Grand R, Michel M L, Vaslin B, Boson B, Janvier G, Aubertin A M, Dormont D, Rivière Y
Abstract excerpt
Following DNA immunization of rhesus macaques with a plasmid encoding the human immunodeficiency virus (HIV)-1 third variable domain (V3) loop, presented by pseudo-viral envelope particles of hepatitis B virus, specific immune responses were induced. The primates were then inoculated with a chimeric simian/human immunodeficiency virus (SHIV). All the animals were infected, but the V3-specific immunization...
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