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Article

Automated genotyping for accurate assignment of the (AT)xNz(AT)y motif within the beta-globin locus control region-hypersensitive site 2.

British journal of haematology - 1 Feb 2001

Tatu T, Thein S

Abstract excerpt

Within the core region of hypersensitive site 2 of the beta-globin locus control region is the (AT)xNz(AT)y motif, which comprises two short tandem repeats of dinucleotide (AT) interrupted by a short variable DNA sequence (Nz). The motif is usually investigated using direct sequence analysis of specifically amplified DNA, but without family studies, phase alignment of the two tandem repeats, occasionally...

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Identifiers

PMID: 11167852
DOI: 10.1046/j.1365-2141.2001.02539.x

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