Article
Towards fully automated genotyping: use of an X linked recessive spastic paraplegia family to test alternative analysis methods.
Human genetics - 1 May 1995
Kobayashi H, Matise T C, Perlin M W, Marks H G, Hoffman E P
Abstract excerpt
Advances in dinucleotide-based genetic maps open possibilities for large scale genotyping at high resolution. The current rate-limiting steps in use of these dense maps is data interpretation (allele definition), data entry, and statistical calculations. We have recently reported automated allele...
Topics
- Alleles
- Automation
- Chromosome Mapping
- DNA
- Female
- Genes, Recessive
- Genetic Carrier Screening
- Genetic Linkage
- Genotype
- Humans
- Lod Score
- Male
- Meiosis
- Pedigree
- Polymerase Chain Reaction
- Spastic Paraplegia, Hereditary
- X Chromosome