Article
The development of Xenopus tropicalis transgenic lines and their use in studying lens developmental timing in living embryos.
Development (Cambridge, England) - 1 May 2000
Offield M F, Hirsch N, Grainger R M
Abstract excerpt
The generation of reporter lines for observing lens differentiation in vivo demonstrates a new strategy for embryological manipulation and allows us to address a long-standing question concerning the timing of the onset of differentiation. Xenopus tropicalis was used to make GFP reporter lines with (gamma)1-crystallin promoter elements directing GFP expression within the early lens. X. tropicalis is a close...
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