Article
Porcine IgA allotypes are not equally transcribed or expressed in heterozygous swine.
Molecular immunology - 1 Aug 2000
Navarro P, Christensen R K, Weber P, Rothschild M, Ekhardt G, Butler J E
Abstract excerpt
The prediction of 1:1 expression of constant region allotypes in heterozygous animals assumes that productive VDJ rearrangements occur at random between chromosomes, switch recombination is random, there is no allele-related defect in switching and there is no selection for a B-cell receptor bearing a certain constant region allotype. In data reported here, this prediction was often not fulfilled for the...
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