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Article

DNA G+C content of the third codon position and codon usage biases of human genes.

Gene - 30 Dec 2000

Sueoka N, Kawanishi Y

Abstract excerpt

The human genome, as in other eukaryotes, has a wide heterogeneity in the DNA base composition. The evolutionary basis for this heterogeneity has been unknown. A previous study of the human genome (846 genes analyzed) has shown that, in the major range of the G+C content in the third codon position (0.25-0.75), biases from the Parity Rule 2 (PR2) among the synonymous codons of the four-codon amino acids are...

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PMID: 11164037
DOI: 10.1016/s0378-1119(00)00480-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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