Article
Epitopes on the dengue 1 virus envelope protein recognized by neutralizing IgM monoclonal antibodies.
Virology - 20 Jan 2001
Beasley D W, Aaskov J G
Abstract excerpt
Three of 41 IgM monoclonal antibodies derived from dengue 1 virus immunized mice neutralized dengue 1 infection in vitro. All three neutralizing monoclonal antibodies reacted with spatially related epitopes on the E protein of dengue 1 which were also recognized by antibodies in sera from dengue patients. Two neutralization-resistant populations of dengue 1 virus, D1-M10 and D1-M17, were selected by sequential...
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