CD95 signaling is not required for the down regulation of cellular responses to systemic Mycobacterium tuberculosis infection.

Abstract excerpt

There is a tendency among tuberculosis patients to have reduced cellular responses to mycobacterial antigens and this loss has been associated with apoptosis of CD4 T cells. In order to determine the role of CD95 in mediating apoptosis of antigen-specific lymphocytes in tuberculosis, mice with a mutated CD95L molecule were infected systemically with virulent Mycobacterium tuberculosis. Both control and CD95L...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Colony Count, Microbial
• Share to Colorimetry