Article
Functional analysis of the putative peroxidase domain of FANCA, the Fanconi anemia complementation group A protein.
Molecular genetics and metabolism - 1 Jan 2001
Ren J, Youssoufian H
Abstract excerpt
Fanconi anemia (FA) is an autosomal recessive disorder manifested by chromosomal breakage, birth defects, and susceptibility to bone marrow failure and cancer. At least seven complementation groups have been identified, and the genes defective in four groups have been cloned. The most common subtype is complementation group A. Although the normal functions of the gene products defective in FA cells are not...
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