Article
X-linked inheritance of Fanconi anemia complementation group B.
Nature genetics - 1 Nov 2004
Meetei Amom Ruhikanta, Levitus Marieke, Xue Yutong, Medhurst Annette L, Zwaan Michel, Ling Chen, Rooimans Martin A, Bier Patrick, Hoatlin Maureen, Pals Gerard, de Winter Johan P, Wang Weidong, Joenje Hans
Abstract excerpt
Fanconi anemia is an autosomal recessive syndrome characterized by diverse clinical symptoms, hypersensitivity to DNA crosslinking agents, chromosomal instability and susceptibility to cancer. Fanconi anemia has at least 11 complementation groups (A, B, C, D1, D2, E, F, G, I, J, L); the genes mutated in 8 of these have been identified. The gene BRCA2 was suggested to underlie complementation group B, but the...
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