Article
Structure-specific abnormalities associated with mutations in a DNA replication accessory factor in Drosophila.
Developmental biology - 15 Feb 2001
Jaffe A B, Jongens T A
Abstract excerpt
We have phenotypically and molecularly analyzed the cutlet locus in Drosophila. Homozygous cutlet flies exhibit abnormal development of a subset of adult tissues, including the eye, wing, and ovary. We show that abnormal development of these tissues is due to a defect in normal cell growth. Surprisingly, cell growth is affected in all developing precursor tissues in cutlet mutant animals, including those that...
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