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Article

Interallelic complementation at the suppressor of forked locus of Drosophila reveals complementation between suppressor of forked proteins mutated in different regions.

Genetics - 1 Apr 1996

Simonelig M, Elliott K, Mitchelson A, O'Hare K

Abstract excerpt

The Su(f) protein of Drosophila melanogaster shares extensive homologies with proteins from yeast (RNA14) and man (77 kD subunit of cleavage stimulation factor) that are required for 3' end processing of mRNA. These homologies suggest that su(f) is involved in mRNA 3' end formation and that some aspects of this process are conserved throughout eukaryotes. We have investigated the genetic and molecular complexity...

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Identifiers

PMID: 8846900
DOI: 10.1093/genetics/142.4.1225
PMCID: PMC1207120

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