Article
A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain.
Nucleic acids research - 15 Feb 2001
Akagi K, Kanai M, Saya H, Kozu T, Berns A
Abstract excerpt
A tetracycline-controlled gene expression system provides a powerful tool to dissect the functions of gene products. However, it often appears difficult to establish cell lines or transgenic animals stably expressing tetracycline-dependent transactivators, possibly as a result of toxicity of the transactivator domains used. In order to overcome this problem, we developed a novel tetracycline-dependent...
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