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Article

The In Vivo Selection Method in Breast Cancer Metastasis

14 Feb 2021

Abstract excerpt

Metastasis is a complex event in cancer progression and causes most deaths from cancer. Repeated transplantation of metastatic cancer cells derived from transplanted murine organs can be used to select the population of highly metastatic cancer cells; this method is called as in vivo selection. The in vivo selection method and highly metastatic cancer cell lines have contributed to reveal the molecular mechanisms...

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PMID: 33672831
DOI: 10.3390/ijms22041886

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