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Article

Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice.

Molecular and cellular biology - 1 Feb 2001

Tong W, Pollard J W

Abstract excerpt

The cell cycle of cultured cells appears to be regulated by opposing actions of the cyclins together with their partners, the cyclin-dependent kinases (Cdk), and their inhibitors (Cki). Consistent with this situation null mutations in the genes for cyclin D1 and Cki p27(Kip1) in mice give opposite phenotypes of dwarfism and gigantism. To test their genetic interactions, we generated mice nullizygous for both...

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Identifiers

PMID: 11158317
DOI: 10.1128/MCB.21.4.1319-1328.2001
PMCID: PMC99584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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