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Article

Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high-incidence community.

Journal of clinical microbiology - 1 Feb 2001

Van Rie A, Warren R, Mshanga I, Jordaan A M, van der Spuy G D, Richardson M, Simpson J, Gie R P, Enarson D A, Beyers N, van Helden P D, Victor T C

Abstract excerpt

Correct and rapid diagnosis is essential in the management of multidrug-resistant tuberculosis (MDR-TB). In this population-based study of 61 patients with drug-resistant tuberculosis, we evaluated the frequency of mutations and compared the performance of genotypic (mutation analysis by dot blot hybridization) and phenotypic (indirect proportion method) drug resistance tests. Three selected codons (rpoB531,...

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Identifiers

PMID: 11158121
DOI: 10.1128/JCM.39.2.636-641.2001
PMCID: PMC87790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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