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Article

Dendritic cells break tolerance and induce protective immunity against a melanocyte differentiation antigen in an autologous melanoma model.

Cancer research - 15 Dec 2000

Schreurs M W, Eggert A A, de Boer A J, Vissers J L, van Hall T, Offringa R, Figdor C G, Adema G J

Abstract excerpt

Tyrosinase-related protein (TRP) 2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. In the current report, we explored the efficacy of nonmutated epitopes with differential binding affinity for MHC class I, derived from mouse TRP2 to induce CTL-mediated, tumor-reactive immunity in vivo within the established B16 melanoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Inhibitory Concentration 50

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Source

Identifiers

PMID: 11156402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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