Article
The angiotensin-converting enzyme genotype and microalbuminuria in autosomal dominant polycystic kidney disease.
Journal of the American Society of Nephrology : JASN - 1 Sept 1999
van Dijk M A, Peters D J, Breuning M H, Chang P C
Abstract excerpt
Autosomal dominant polycystic kidney disease (AD-PKD) has a variable clinical course. Clinical parameters associated with a worse prognosis are hypertension and proteinuria or microalbuminuria (MA). Because chronic stimulation of the renin-angiotensin system is likely to be present in ADPKD patients, the effect of the angiotensin-converting enzyme insertion/deletion (ACE I/D) genotype on the variability of these...
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