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Article

Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes

1 Jan 2001

Abstract excerpt

Individual susceptibility to carcinogens, an important determinant of disease risk, is influenced by host factors such as the ability to repair DNA lesions. In order to identify subjects who are at high risk, we have developed a microgel electrophoresis assay for use in molecular epidemiological studies. The assay was validated in a pilot case-control study: Peripheral blood lymphocytes were collected from 100...

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PMID: 11139596
DOI: 10.1093/mutage/16.1.25

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