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Article

Evidence for Positive Selection in Foot-and-Mouth Disease Virus Capsid Genes From Field Isolates

1 Jan 2001

Abstract excerpt

The nature of selection on capsid genes of foot-and-mouth disease virus (FMDV) was characterized by examining the ratio of nonsynonymous to synonymous substitutions in 11 data sets of sequences obtained from six different serotypes of FMDV. Using a method of analysis that assigns each codon position to one of a number of estimated values of nonsynonymous to synonymous ratio, significant evidence of positive...

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PMID: 11139487
DOI: 10.1093/genetics/157.1.7

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