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Article

Crystal structure of the Holliday junction resolving enzyme T7 endonuclease I.

Nature structural biology - 1 Jan 2001

Hadden J M, Convery M A, Déclais A C, Lilley D M, Phillips S E

Abstract excerpt

We have solved the crystal structure of the Holliday junction resolving enzyme T7 endonuclease I at 2.1 A resolution using the multiwavelength anomalous dispersion (MAD) technique. Endonuclease I exhibits strong structural specificity for four-way DNA junctions. The structure shows that it forms a symmetric homodimer arranged in two well-separated domains. Each domain, however, is composed of elements from both...

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Identifiers

PMID: 11135673
DOI: 10.1038/83067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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