Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The phosphotyrosyl phosphatase activator, Ncs1p (Rrd1p), functions with Cla4p to regulate the G(2)/M transition in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jan 2001

Mitchell D A, Sprague G F

Abstract excerpt

The Saccharomyces cerevisiae p21-activated kinases, Ste20p and Cla4p, have individual functions but appear to share an essential function(s) as well because a strain lacking both kinases is inviable. To learn more about the shared function, we sought new mutations that were lethal in the absence of CLA4. This approach led to the identification of at least 10 complementation groups designated NCS (need CLA4 to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CDC28 Protein Kinase, S cerevisiae
Share to G2 Phase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Genes, Lethal

Share to Mitosis

Share to Peptidylprolyl Isomerase

Share to Phosphoprotein Phosphatases

Share to Protein Phosphatase 2

Source

Open in PubMed Open full text

Identifiers

PMID: 11134337
DOI: 10.1128/MCB.21.2.488-500.2001
PMCID: PMC86606

Genes

NCS1
PTPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The phosphotyrosyl phosphatase activator, Ncs1p (Rrd1p), functions with Cla4p to regulate the G(2)/M transition in Saccharomyces cerevisiae.PMID 11134337Read ↗

The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.Semantic proximity Read ↗

Synthetic lethal analysis implicates Ste20p, a p21-activated potein kinase, in polarisome activation.Semantic proximity Read ↗

The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions.Semantic proximity Read ↗

Septins, under Cla4p regulation, and the chitin ring are required for neck integrity in budding yeast.Semantic proximity Read ↗

Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.Semantic proximity Read ↗

The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate.Semantic proximity Read ↗

Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle.Semantic proximity Read ↗

The role of Stn1p in Saccharomyces cerevisiae telomere capping can be separated from its interaction with Cdc13p.Semantic proximity Read ↗

Functional distinction between Cln1p and Cln2p cyclins in the control of the Saccharomyces cerevisiae mitotic cycle.Semantic proximity Read ↗

Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic analysis of Mps3 SUN domain mutants in Saccharomyces cerevisiae reveals an interaction with the SUN-like protein Slp1.Semantic proximity Read ↗

Implications of maintenance of mother-bud neck size in diverse vital processes of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.