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Article

The lipoprotein lipase Ser447Ter mutation and risk of stroke in the Chinese.

Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2003

Zhao Shui-Ping, Tong Qi-Guang, Xiao Zhi-Jie, Cheng Yan-Chun, Zhou Hong-Nian, Nie Shai

Abstract excerpt

BACKGROUND: Lipoprotein lipase (LPL) plays an important role in plasma lipoprotein metabolism. The Ser447Ter mutation of LPL may be associated with ischemic cerebrovascular diseases. We investigated whether the LPL variants were related to risk of strokes in Chinese Hans. METHODS: We recruited 160 patients with cerebrovascular diseases (ischemic stroke, n=96; hemorrhagic stroke, n=64) and 117 age-matched...

Topics

Aged
Alleles
Asian People
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Lipids
Lipoprotein Lipase
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymorphism, Single Nucleotide

Risk Factors

Stroke

Source

Identifiers

PMID: 12636935
DOI: 10.1016/s0009-8981(03)00016-0

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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