Article
[Genetics of bipolar affective disorders. Current status of research for identification of susceptibility genes].
Der Nervenarzt - 1 Jul 2002
Schumacher J, Cichon S, Rietschel M, Nöthen M M, Propping P
Abstract excerpt
Bipolar affective disorder is a highly heritable condition, as evidenced by twin, family, and adoption studies. However, the mode of inheritance is complex and linkage findings have been difficult to replicate. Despite these limitations, consistent linkage findings have emerged for several chromosomes, notably 3p12-p14, 4p16, 10q25-q26, and 12q23-q24. Three additional areas, 13q32-q33, 18p11-q11, and 22q12-q13,...
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