Article
Darier's disease: a new paradigm for genetic studies in psychiatric disorders.
Sao Paulo medical journal = Revista paulista de medicina - 9 Nov 2000
Cordeiro Q, Werebe D M, Vallada H
Abstract excerpt
CONTEXT: One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes. CASE REPORT: A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be...
Topics
- Adult
- Chromosome Segregation
- Chromosomes, Human, Pair 12
- Darier Disease
- Depression
- Genetic Predisposition to Disease
- Humans
- Male
- Mood Disorders
- Pedigree
