Article
Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease.
Molecular psychiatry - 1 Jan 2002
Jones I, Jacobsen N, Green E K, Elvidge G P, Owen M J, Craddock N
Abstract excerpt
Darier's disease is a rare autosomal dominantly inherited keratosis.(1) We have previously reported a family in which major affective disorder co-segregated with Darier's disease, consistent with linkage between the Darier gene and a susceptibility locus for affective illness (max lod = 2.1).(2) The Darier gene has been mapped to 12q 23-q24.1 and identified as ATP2A2, a gene encoding SERCA2-a...
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