Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

COL9A2 allelotypes in intervertebral disc disease.

Biochemical and biophysical research communications - 20 Dec 2000

Wrocklage C, Wassmann H, Paulus W

Abstract excerpt

An allelic variation of the COL9A2 gene encoding the alpha(2)-chain of collagen IX has recently been identified as a genetic risk factor for intervertebral disc prolapse, resulting in a tryptophane (Trp) substitution at position 326 of the protein. To enable quick screening of a large population we established a single enzyme (BsmFI) restriction assay which was validated by screening disc tissue samples of 250...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Collagen
Share to Collagen Type IX

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Restriction-Modification Enzymes

Share to Intervertebral Disc

Share to Intervertebral Disc Displacement

Share to Restriction Mapping

Share to Tryptophan

Source

Identifiers

PMID: 11118298
DOI: 10.1006/bbrc.2000.3967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

COL9A2 allelotypes in intervertebral disc disease.PMID 11118298Read ↗

An allele of COL9A2 associated with intervertebral disc disease.Semantic proximity Read ↗

The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration.Semantic proximity Read ↗

Identification of a novel common genetic risk factor for lumbar disk disease.Semantic proximity Read ↗

Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis.Semantic proximity Read ↗

The role of collagen IX tryptophan polymorphisms in symptomatic intervertebral disc disease in Southern European patients.Semantic proximity Read ↗

Association between COL9A2 Gln326Arg mutations and the development of intervertebral disc disease in a Chinese population.Semantic proximity Read ↗

Current evidence for a modulation of low back pain by human genetic variants.Semantic proximity Read ↗

Association study of COL9A2 with lumbar disc disease in the Japanese population.Semantic proximity Read ↗

The role of polymorphisms of genes encoding collagen IX and XI in lumbar disc diseaseSemantic proximity Read ↗

Expression of the Trp2 allele of COL9A2 is associated with alterations in the mechanical properties of human intervertebral discs.Semantic proximity Read ↗

Association between polymorphisms of collagen genes and susceptibility to intervertebral disc degeneration: a meta-analysis.Semantic proximity Read ↗

A novel missense COL9A3 variant in a pedigree with multiple lumbar disc herniation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.