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Article

The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration.

Spine - 15 Dec 2005

Jim Jeffrey J T, Noponen-Hietala Noora, Cheung Kenneth M C, Ott Jürg, Karppinen Jaro, Sahraravand Ahmad, Luk Keith D K, Yip Shea-Ping, Sham Pak C, Song You-Qiang, Leong John C Y, Cheah Kathryn S E, Ala-Kokko Leena, Chan Danny

Abstract excerpt

STUDY DESIGN: Low back pain (LBP) and sciatica are usually caused by degenerative disc disease (DDD). Although they are common, the etiology of these conditions is poorly understood. A large population case-control study in the Southern Chinese was performed to study genetic risk factors to DDD. OBJECTIVES: To gain a better understanding of the etiology of DDD in relation to structural defects of the...

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Source

Identifiers

PMID: 16371896
DOI: 10.1097/01.brs.0000190828.85331.ef

Genes

LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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