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Article

Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis.

Annals of the rheumatic diseases - 1 Dec 2003

Noponen-Hietala N, Kyllönen E, Männikkö M, Ilkko E, Karppinen J, Ott J, Ala-Kokko L

Abstract excerpt

BACKGROUND: Degenerative lumbar spinal stenosis (LSS) is usually caused by disc herniation or degeneration. Several genetic factors have been implicated in disc disease. Tryptophan alleles in COL9A2 and COL9A3 have been shown to be associated with lumbar disc disease in the Finnish population, and polymorphisms in the vitamin D receptor gene (VDR) (FokI and TaqI), the matrix metalloproteinase-3 gene (MMP-3) and...

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Identifiers

PMID: 14644861
DOI: 10.1136/ard.2003.008334
PMCID: PMC1754404

Genes

LSS
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis.PMID 14644861Read ↗

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