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Article

Current evidence for a modulation of low back pain by human genetic variants.

Journal of cellular and molecular medicine - 1 Aug 2009

Tegeder Irmgard, Lötsch Jörn

Abstract excerpt

The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration or the immune response and genes involved in pain perception, signalling and psychological processing. This inter-individual variability which is partly due to...

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Source

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Identifiers

PMID: 19228264
DOI: 10.1111/j.1582-4934.2009.00703.x
PMCID: PMC6529970

Genes

MMP3
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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