Article
Expression of the Trp2 allele of COL9A2 is associated with alterations in the mechanical properties of human intervertebral discs.
Spine - 1 Dec 2007
Aladin Darwesh M K, Cheung Kenneth M C, Chan Danny, Yee Anita F Y, Jim Jeffrey J T, Luk Keith D K, Lu William W
Abstract excerpt
STUDY DESIGN: Biomechanical study into the association between genetic polymorphism in COL9A2 and mechanical properties of human nucleus pulposus. OBJECTIVE: To examine whether there is an association between genetic polymorphism in a structural gene, and alterations in the mechanical properties of the intervertebral discs that may predispose to disc degeneration. SUMMARY OF BACKGROUND DATA: Genetic studies have...
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