Article
Prandial glucose effectiveness and fasting gluconeogenesis in insulin-resistant first-degree relatives of patients with type 2 diabetes.
Diabetes - 1 Dec 2000
Nielsen M F, Nyholm B, Caumo A, Chandramouli V, Schumann W C, Cobelli C, Landau B R, Rizza R A, Schmitz O
Abstract excerpt
Impaired glucose effectiveness (i.e., a diminished ability of glucose per se to facilitate its own metabolism), increased gluconeogenesis, and endogenous glucose release are, together with insulin resistance and beta-cell abnormalities, established features of type 2 diabetes. To explore aspects of the pathophysiology behind type 2 diabetes, we assessed in a group of healthy people prone to develop type 2...
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